Do Melanoidins Induced by Topical 9% Dihydroxyacetone Sunless Tanning Spray Inhibit Vitamin D Production? A Pilot Study

• Published in: Photochemistry and photobiology Vol. 85; no. 5; pp. 1265 - 1266
• Main Authors: Armas, Laura A. G., Fusaro, Ramon M., Sayre, Robert M., Huerter, Christopher J., Heaney, Robert P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2009
• Subjects: Administration, Topical; Dihydroxyacetone - administration & dosage; Female; Humans; Light therapy; Pilot Projects; Polymers - administration & dosage; Skin care products; Ultraviolet radiation; Vitamin D; Vitamin D - antagonists & inhibitors; Vitamin D - biosynthesis
• ISSN: 0031-8655; 1751-1097
• DOI: 10.1111/j.1751-1097.2009.00574.x

We report here preliminary pilot study data of the effect of sunless tanning spray with 9% [Correction added after online publication (August 24th, 2009): The concentration of Dihydroxyacetone used in the study was 9% and not 3% as previously stated] dihydroxyacetone (DHA) on 25‐hydroxyvitamin D [25(OH)D] serum levels in subjects exposed to controlled amounts of UV‐B radiation during April/May in Omaha, NE, 41°N latitude. We found that DHA‐induced melanoidins in skin act as a topical sunscreen attenuating the formation of 25(OH)D.