UVB suppresses PTEN expression by upregulating miR-141 in HaCaT cells

• Published in: Journal of biomedical research Vol. 25; no. 2; pp. 135 - 140
• Main Authors: Li, Wei, Di, Wu, Hua, Lijuan, Zhou, Bingrong, Guo, Ze, Luo, Dan
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.03.2011; Editorial Department of Journal of Biomedical Research
• Subjects: apoptosis; HaCaT cells; HaCaT细胞; MicroRNA-141; miRNAs; PTEN; Research Paper; UVB; 基因表达水平; 小分子RNA; 异硫氰酸荧光素; 非编码RNA; UVB; PTEN; apoptosis; MicroRNA-141; HaCaT cells

MicroRNAs （miRNAs） are 21 to 24 nucleotide, non-coding RNA molecules that post-transcriptionally regulate the expression of target genes. Ultraviolet B （UVB） radiation has been shown to inhibit phosphatase and tensin homolog deleted on chromosome 10 （PTEN） expression in HaCaT cells through an unknow...