Sertoli-Leydig Cell Tumour in a Postmenopausal Woman Showing all Facets of the Insulin Resistance Syndrome (IRS)

Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of <0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased...

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Published inUpsala journal of medical sciences Vol. 110; no. 3; pp. 233 - 236
Main Authors Dahlgren, Eva, Gull, Berit, Willén, Roger, Sundler, Frank, Rosén, Thord, Jansson, Per-Anders
Format Journal Article
LanguageEnglish
Published England Informa UK Ltd 2005
Taylor & Francis
Subjects
Basic Medicine
Cell and Molecular Biology
Cell- och molekylärbiologi
exoaenous insulin treatment
Female
Humans
Immunohistochemistry
Insulin Resistance
Medical and Health Sciences
Medicin och hälsovetenskap
Medicinska och farmaceutiska grundvetenskaper
metabolic syndrome
Middle Aged
Postmenopause - physiology
Sertoli-Leydig Cell Tumor - complications
Sertoli-Leydig Cell Tumor - pathology
Sertoli-Leydig cell tumour
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Summary:Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of <0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels due to a Sertoli-Leydig cell tumour. This is the first case to suggest an association between IRS and Sertoli-Leydig cell tumours. Furthermore, we highlight the difficulties in detecting this ovarian tumour with sonography.
Bibliography:ObjectType-Case Study-2
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ISSN:0300-9734
2000-1967
DOI:10.3109/2000-1967-068