Phenolic and Nonpolar Fractions of Elaeagnus rhamnoides (L.) A. Nelson Extracts as Virulence Modulators-In Vitro Study on Bacteria, Fungi, and Epithelial Cells

• Published in: Molecules (Basel, Switzerland) Vol. 23; no. 7; p. 1498
• Main Authors: Różalska, Barbara, Sadowska, Beata, Żuchowski, Jerzy, Więckowska-Szakiel, Marzena, Budzyńska, Aleksandra, Wójcik, Urszula, Stochmal, Anna
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.06.2018; MDPI
• Subjects: Adhesion; Adhesion tests; Aerosols; Anti-Infective Agents - isolation & purification; Anti-Infective Agents - pharmacology; Antimicrobial activity; Antimicrobial agents; antivirulence properties; Bacteria; Biocides; Biocompatibility; Biofilms; Biology; Butanol; Caco-2 Cells; Candida - drug effects; Candida - growth & development; Candida - pathogenicity; Cell Line; Cell Survival - drug effects; Chemical composition; Collagen; Conditioning; Cytotoxicity; Dietary supplements; Elaeagnaceae - chemistry; Elaeagnus rhamnoides; Elaeagnus rhamnoides butanol extracts; Environmental protection; Epithelial cells; Fibrinogen; Fibroblasts - cytology; Fibroblasts - drug effects; Fluorescein; Fluorescein isothiocyanate; Formulations; Fruit - chemistry; Fruits; Fungi; Fungicides; Gram-negative bacteria; Gram-Negative Bacteria - drug effects; Gram-Negative Bacteria - growth & development; Gram-Negative Bacteria - pathogenicity; Gram-Positive Bacteria - drug effects; Gram-Positive Bacteria - growth & development; Gram-Positive Bacteria - pathogenicity; Humans; Immunology; In vivo methods and tests; Liquid-Liquid Extraction - methods; Medical practices; Microbial Sensitivity Tests; Microbiota; Microorganisms; Morphogenesis; nonpolar fractions; Organic chemistry; Pathogens; phenolic; Phenolic compounds; Phenols; Phenols - chemistry; Phenols - isolation & purification; Plant Extracts - isolation & purification; Plant Extracts - pharmacology; Plant Leaves - chemistry; Plant Stems - chemistry; Saliva; Saponins - chemistry; Saponins - isolation & purification; Soil sciences; Staphylococcus aureus; Stem cells; Triterpenes - chemistry; Triterpenes - isolation & purification; Virulence; Virulence - drug effects; nonpolar fractions; antivirulence properties; Elaeagnus rhamnoides butanol extracts; phenolic

Butanol extracts from leaves, twigs, and fruits of (L.) A. Nelson (sea buckthorn, SBT) were fractionated into phenolic and nonpolar lipid components, the chemical composition of which was analyzed. Assuming that an effect on natural microbiota and host epithelial cells needs to be assessed, regardle...