New Chemical Constituents from the Bark of Dendropanax morbifera Leveille and their Evaluation of Antioxidant Activities

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 21; p. 3967
• Main Authors: Chung, Ill-Min, Kim, Seung-Hyun, Kwon, Chang, Kim, So-Yeon, Yang, Yu-Jin, Kim, Ju-Sung, Ali, Mohd, Ahmad, Ateeque
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.11.2019; MDPI
• Subjects: Antioxidants; Antioxidants - chemistry; Antioxidants - classification; Araliaceae - chemistry; Bark; Carbon; Constituents; Cytotoxicity; Dendropanax morbifera; dpph; Fatty Acids - chemistry; Fatty Acids - isolation & purification; Glycosides - chemistry; Glycosides - isolation & purification; Guaiacol; Mass spectrometry; Molecular Structure; new and known compounds; NMR; Nuclear magnetic resonance; Olein; Plant Bark - chemistry; Plant Extracts - chemistry; Plant Extracts - pharmacology; reducing power phosphomolybdenum activities; Saponins - chemistry; Saponins - isolation & purification; Scientific imaging; structure determination; Sugar; Triterpenes - chemistry; Triterpenes - classification; Triterpenes - isolation & purification; Xylopyranoside; NO; DPPH; Structure determination; reducing power phosphomolybdenum activities; New and known compounds
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules24213967

Four new constituents, as c -6-oxogeran-4-enyl-10-oxy- -β-arabinopyranosyl-4'- -β-arabinopyranosyl-2''-octadec-9''',12''',15'''-trienoate ( ), geran-3(10)-enyl-1-oxy- -β-arabinopyranosyl-4'- -β-arabinopyranosyl-2''-octadec-9''',12''',15'''-trienoate ( ), geranilan-8-oxy- - -d-xylopyranosyl-2'- -octadec-9'',12'',15''-trienoate ( ), 1-cyclohex-2', 5'-dienyl 1-cyclohexylethanol- -β-d-xylopyranoside ( ), along with six known constituents, guaiacol- -β-d-arabinopyaranoside ( ), -tetradecanyl oleate ( ), oleyl- β-d-xyloside ( ), -octadec-9,12-dienoyl- -β-d-arabinopyranoside ( ), linolenyl- -β-d-arabinofuranoside ( ) andglyceryl-1,3-dipalmito-2-olein ( ), were isolated and identified from the bark. The new structures were established by one-and two-dimensional NMR (and in combination with IR, FAB-MSand HR-ESI-FTMS. The comparative evaluation of antioxidant potential by phosphomolybdenum, DPPH, FRAP and the NO assay of four different compounds ( - ), we have found that the compounds 1 and 2 have power as a natural antioxidant, whereas the compound and exhibited mild activity in comparison to compounds and .