Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review

Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing...

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Published inMolecules (Basel, Switzerland) Vol. 26; no. 20; p. 6123
Main Authors Xu, Fa-Wei, Lv, Ying-Li, Zhong, Yu-Fan, Xue, Ya-Nan, Wang, Yong, Zhang, Li-Yun, Hu, Xian, Tan, Wei-Qiang
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 11.10.2021
MDPI
Subjects
Adhesives
angiogenesis
Animals
Anti-Bacterial Agents - pharmacology
Anti-Infective Agents - pharmacology
anti-inflammation
antifibrosis
Antioxidants
Antioxidants - pharmacology
Bandages - trends
Biocompatibility
Biomedical materials
Catechin - analogs & derivatives
Catechin - metabolism
Catechin - pharmacology
Cellulose
Chemokines
Cicatrix - prevention & control
Cytokines
EGCG
Epidermal growth factor
Humans
Hyaluronic acid
Hydrogels
Hydrogels - pharmacology
Inflammation
Keratin
Nanoparticles
Neutrophils
Physical properties
Polymers
Polyphenols
Review
Skin
Skin - drug effects
Skin - metabolism
skin wound healing
Tea
Tea - metabolism
wound dressing
Wound healing
Wound Healing - drug effects
Wound Healing - physiology
anti-inflammation
antifibrosis
wound dressing
EGCG
angiogenesis
skin wound healing
Online AccessGet full text

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Abstract Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.
AbstractList Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.
Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.
Author Hu, Xian
Zhang, Li-Yun
Xue, Ya-Nan
Xu, Fa-Wei
Zhong, Yu-Fan
Wang, Yong
Lv, Ying-Li
Tan, Wei-Qiang
AuthorAffiliation 1 Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, China; xufawei@zju.edu.cn (F.-W.X.); 12018261@zju.edu.cn (Y.-F.Z.); xueyanan2020@zju.edu.cn (Y.-N.X.); wongyong@zju.edu.cn (Y.W.); 18868735326@163.com (L.-Y.Z.); huxiandxg@163.com (X.H.)
2 Tea Research Institute, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310013, China; 3180100543@zju.edu.cn
AuthorAffiliation_xml – name: 2 Tea Research Institute, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310013, China; 3180100543@zju.edu.cn
– name: 1 Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, China; xufawei@zju.edu.cn (F.-W.X.); 12018261@zju.edu.cn (Y.-F.Z.); xueyanan2020@zju.edu.cn (Y.-N.X.); wongyong@zju.edu.cn (Y.W.); 18868735326@163.com (L.-Y.Z.); huxiandxg@163.com (X.H.)
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/34684703$$D View this record in MEDLINE/PubMed
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2021 by the authors. 2021
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Keywords anti-inflammation
antifibrosis
wound dressing
EGCG
angiogenesis
skin wound healing
Language English
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Snippet Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound...
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SubjectTerms Adhesives
angiogenesis
Animals
Anti-Bacterial Agents - pharmacology
Anti-Infective Agents - pharmacology
anti-inflammation
antifibrosis
Antioxidants
Antioxidants - pharmacology
Bandages - trends
Biocompatibility
Biomedical materials
Catechin - analogs & derivatives
Catechin - metabolism
Catechin - pharmacology
Cellulose
Chemokines
Cicatrix - prevention & control
Cytokines
EGCG
Epidermal growth factor
Humans
Hyaluronic acid
Hydrogels
Hydrogels - pharmacology
Inflammation
Keratin
Nanoparticles
Neutrophils
Physical properties
Polymers
Polyphenols
Review
Skin
Skin - drug effects
Skin - metabolism
skin wound healing
Tea
Tea - metabolism
wound dressing
Wound healing
Wound Healing - drug effects
Wound Healing - physiology
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Title Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review
URI https://www.ncbi.nlm.nih.gov/pubmed/34684703
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