Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review

Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 26; no. 20; p. 6123
Main Authors Xu, Fa-Wei, Lv, Ying-Li, Zhong, Yu-Fan, Xue, Ya-Nan, Wang, Yong, Zhang, Li-Yun, Hu, Xian, Tan, Wei-Qiang
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 11.10.2021
MDPI
Subjects
Adhesives
angiogenesis
Animals
Anti-Bacterial Agents - pharmacology
Anti-Infective Agents - pharmacology
anti-inflammation
antifibrosis
Antioxidants
Antioxidants - pharmacology
Bandages - trends
Biocompatibility
Biomedical materials
Catechin - analogs & derivatives
Catechin - metabolism
Catechin - pharmacology
Cellulose
Chemokines
Cicatrix - prevention & control
Cytokines
EGCG
Epidermal growth factor
Humans
Hyaluronic acid
Hydrogels
Hydrogels - pharmacology
Inflammation
Keratin
Nanoparticles
Neutrophils
Physical properties
Polymers
Polyphenols
Review
Skin
Skin - drug effects
Skin - metabolism
skin wound healing
Tea
Tea - metabolism
wound dressing
Wound healing
Wound Healing - drug effects
Wound Healing - physiology
anti-inflammation
antifibrosis
wound dressing
EGCG
angiogenesis
skin wound healing
Online AccessGet full text

Cover

More Information
Summary:Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
These authors contributed equally to this work.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules26206123