Lipase-catalyzed Solvent-free Synthesis of Polyglycerol 10 (PG-10) Esters

Polyglycerol fatty acid esters, which have been widely used as emulsifiers in food, medicine and cosmetics industries, were the subject of solvent-free enzymatic synthesis in this study. There have been previous reports on enzymatic synthesis of various polyglycerol esters; however, this investigati...

Full description

Saved in:
Bibliographic Details
Published inChemical and Biochemical Engineering Quarterly Vol. 33; no. 4; pp. 501 - 509
Main Authors Satyawali, Yamini, Cawenberghs, Lieve, Dejonghe, Winnie
Format Journal Article Paper
LanguageEnglish
Published Croatian Association of Chemical Engineers 2020
Hrvatsko društvo kemijskih inženjera i tehnologa
Croatian Society of Chemical Engineers
Subjects
Backup software
Cosmetics industry
Enzymes
Esters
Fatty acids
Lipase
PG-10
Phenolphthalein
polyglycerol
solvent free synthesis
Online AccessGet full text

Cover

More Information
Summary:Polyglycerol fatty acid esters, which have been widely used as emulsifiers in food, medicine and cosmetics industries, were the subject of solvent-free enzymatic synthesis in this study. There have been previous reports on enzymatic synthesis of various polyglycerol esters; however, this investigation extends the synthesis to PG-10 esters. The effects of substrate molar ratio, addition of emulsifiers to enhance mixing, and addition of molecular sieves or N2 flushing for water removal, was investigated. The solvent-free synthesis using N2 flushing leads to complete conversion of fatty acid, yielding a completely acid free product. The synthesis is validated for polyglycerol laurate and polyglycerol caprylate, both useful products in the cosmetic industry.
Bibliography:232518
ISSN:0352-9568
1846-5153
DOI:10.15255/CABEQ.2019.1702