Perventricular double-device closure of wide-spaced multi-hole perimembranous ventricular septal defect

• Published in: Journal of cardiothoracic surgery Vol. 12; no. 1; p. 24
• Main Authors: Liang, Fei, Hongxin, Li, Zhang, Hai-Zhou, Wenbin, Guo, Zou, Cheng-Wei, Farhaj, Zeeshan
• Format: Journal Article
• Language: English
• Published: England BioMed Central 17.04.2017; BMC
• Subjects: Adolescent; Adult; Bundling; Bypasses; Cardiac Catheterization - methods; Cardiac Surgical Procedures - instrumentation; Child; Child, Preschool; Complications; Defects; Device closure; Echocardiography; Equipment Design; Feasibility studies; Female; Follow-Up Studies; Heart; Heart Septal Defects, Ventricular - diagnosis; Heart Septal Defects, Ventricular - surgery; Humans; Implantation; Infant; Male; Occlusion; Ostomy; Patients; Perimembranous ventricular septal defect; Perventricular; Radiography, Thoracic; Retrospective Studies; Septal Occluder Device; Shunts; Treatment Outcome; Ventricle; Young Adult; Perimembranous ventricular septal defect; Echocardiography; Device closure; Perventricular
• ISSN: 1749-8090; 1749-8090
• DOI: 10.1186/s13019-017-0585-5

Device closure of a wide-spaced multi-hole PmVSD is difficult to succeed in percutaneous approach. This study is to evaluate the feasibility, safety and efficacy of perventricular device closure of wide-spaced multi-hole PmVSD using a double-device implanting technique. Sixteen patients with wide-spaced multi-hole PmVSD underwent perventricular closure with two devices through an inferior median sternotomy approach under transesophageal echocardiographic guidance. The largest hole and its adjacent small holes were occluded with an optimal-sized device. The far-away residual hole was occluded with the other device using a probe-assisted delivery system. All patients were followed up for a period of 1 to 4 years to determine the residual shunt, atrioventricular block and the adjacent valvular function. The number of the holes of the PmVSD was 2 to 4. The maximum distance between the holes was 5.0 to 10.0 mm (median, 6.4 mm). The diameter of the largest hole was 2.5 to 7.0 mm (median, 3.6 mm). The success rate of double-device closure was 100%. Immediate residual shunts were found in 6 patients (38%), and incomplete right bundle branch block at discharge occurred in 3 cases (19%). Both complications decreased to 6% at 1-year follow-up. Neither of them had a severe device-related complication. Perventricular closure of a wide-spaced multi-hole PmVSD using a double-device implanting technique is feasible, safe, and efficacious. In multi-hole PmVSDs with the distance between the holes of more than 5 mm, double-device implantation may achieve a complete occlusion.