Revisiting the Chemistry of Vinylpyrazoles: Properties, Synthesis, and Reactivity

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 11; p. 3493
• Main Authors: Silva, Vera L. M., Silva, Artur M. S.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.05.2022; MDPI
• Subjects: biological activity; Catalysis; pyrazoles; reactivity; Reagents; Review; synthesis; vinylpyrazoles; synthesis; reactivity; biological activity; pyrazoles; vinylpyrazoles

Vinylpyrazoles, also known as pyrazolyl olefins, are interesting motifs in organic chemistry but have been overlooked. This review describes the properties and synthetic routes of vinylpyrazoles and highlights their versatility as building blocks for the construction of more complex organic molecule...