Two Novel Proline-Containing Catechin Glucoside from Water-Soluble Extract of Codonopsis pilosula

Choushenflavonoids A ( ) and B ( ), two unusual proline-containing catechin glucosides, were isolated from the roots of cultivated in a high-altitude location of Yunnan province. Their structures were determined by spectroscopic data and chemical methods. Specifically, the absolute configuration of...

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Published inMolecules (Basel, Switzerland) Vol. 23; no. 1; p. 180
Main Authors Qin, Fu-Ying, Cheng, Li-Zhi, Yan, Yong-Ming, Liu, Bao-Hua, Cheng, Yong-Xian
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 16.01.2018
MDPI
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Summary:Choushenflavonoids A ( ) and B ( ), two unusual proline-containing catechin glucosides, were isolated from the roots of cultivated in a high-altitude location of Yunnan province. Their structures were determined by spectroscopic data and chemical methods. Specifically, the absolute configuration of glucose residue in and was assigned by acid hydrolysis followed by derivatization and gas chromatography (GC) analysis. In addition, biological evaluation of and against Sirtuin 1 (SIRT1) was carried out.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23010180