Extracellular Matrix Revisited: Roles in Tissue Engineering

The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability, and biochemical cues necessary for tissue morphogenesis and homeostasis. This review highlights some of the recen...

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Published inInternational neurourology journal Vol. 20; no. Suppl 1; pp. S23 - 29
Main Authors Kim, Youhwan, Ko, Hyojin, Kwon, Ik Keun, Shin, Kwanwoo
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Continence Society 01.05.2016
대한배뇨장애요실금학회
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ISSN2093-6931
2093-4777
2093-6931
DOI10.5213/inj.1632600.318

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Summary:The extracellular matrix (ECM) is a heterogeneous, connective network composed of fibrous glycoproteins that coordinate in vivo to provide the physical scaffolding, mechanical stability, and biochemical cues necessary for tissue morphogenesis and homeostasis. This review highlights some of the recently raised aspects of the roles of the ECM as related to the fields of biophysics and biomedical engineering. Fundamental aspects of focus include the role of the ECM as a basic cellular structure, for novel spontaneous network formation, as an ideal scaffold in tissue engineering, and its essential contribution to cell sheet technology. As these technologies move from the laboratory to clinical practice, they are bound to shape the vast field of tissue engineering for medical transplantations.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
G704-001728.2016.20..007
ISSN:2093-6931
2093-4777
2093-6931
DOI:10.5213/inj.1632600.318