Duodenal Adenocarcinoma of Brunner Gland Origin: A Case Report

We report a case of adenocarcinoma originating from the duodenal Brunner glands in a 47-year-old female patient. The lesion was 0.8 cm in extent and located at the posterior wall of the first part of the duodenum. Histologically, the tumor showed transition from non-neoplastic Brunner glands through...

Full description

Saved in:
Bibliographic Details
Published inJournal of pathology and translational medicine Vol. 52; no. 3; pp. 179 - 182
Main Authors Moon, Ji Hye, Lee, Kyoungbun, Yang, Han-Kwang, Kim, Woo Ho
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Society of Pathologists and the Korean Society for Cytopathology 01.05.2018
Korean Society of Pathologists & the Korean Society for Cytopathology
대한병리학회
Subjects
Adenocarcinoma
Brunner glands
Case Study
Duodenum
병리학
Adenocarcinoma
Duodenum
Brunner glands
Online AccessGet full text
ISSN2383-7837
2383-7845
DOI10.4132/jptm.2017.10.09

Cover

More Information
Summary:We report a case of adenocarcinoma originating from the duodenal Brunner glands in a 47-year-old female patient. The lesion was 0.8 cm in extent and located at the posterior wall of the first part of the duodenum. Histologically, the tumor showed transition from non-neoplastic Brunner glands through dysplastic epithelium into adenocarcinoma. The carcinoma cells were strongly positive for MUC6 protein, which is an epithelial marker for the Brunner glands. Tumor protein p53 was overexpressed in the carcinoma cells, but not in the non-neoplastic or dysplastic epithelium. Dystrophic calcification was predominant. This is the first case report of duodenal adenocarcinoma of Brunner gland origin in Korea.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2383-7837
2383-7845
DOI:10.4132/jptm.2017.10.09