Thermal Degradation Kinetics and pH-Rate Profiles of Iriflophenone 3,5-C-β-d-diglucoside, Iriflophenone 3-C-β-d-Glucoside and Mangiferin in Aquilaria crassna Leaf Extract

• Published in: Molecules (Basel, Switzerland) Vol. 25; no. 21; p. 4898
• Main Authors: Wongwad, Eakkaluk, Ingkaninan, Kornkanok, Wisuitiprot, Wudtichai, Sritularak, Boonchoo, Waranuch, Neti
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.10.2020; MDPI
• Subjects: Activation energy; Antioxidants; Aquilaria crassna; Arrhenius plot; Bioactive compounds; Food production; Food products; Glucosides; Glucosides - chemistry; Hydrocarbons; Hydrogen-Ion Concentration; Kinetics; Leaves; pH-rate profile; Plant extracts; Plant Extracts - chemistry; Plant Leaves - chemistry; Plant Lectins - chemistry; Polyphenols; Reaction kinetics; Regression analysis; Shelf life; Stability analysis; Temperature; Thermal degradation; thermal degradation kinetics; Thymelaeaceae - chemistry; Xanthones - chemistry; pH-rate profile; Aquilaria crassna; thermal degradation kinetics; Arrhenius plot
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules25214898

The health benefits of the Pierre ex Lecomte leaf extract (AE) make it very useful as an ingredient in food and pharmaceutical products. Iriflophenone 3,5- - -d-diglucoside ( ), iriflophenone 3- - -d-glucoside ( ) and mangiferin ( ) are bioactive compounds of AE. We assessed the stability of AE by investigating the thermal degradation kinetics and shelf-life ( ) of compounds , and using Arrhenius plot models and studied their pH-rate profiles. The results demonstrate that and were degraded, following a first-order kinetic reaction. The degradation of followed first-order reaction kinetics when present in a solution and second-order reaction kinetics in the dried powder form of the extract. According to the first-order kinetic model, the predicted shelf-life ( ) of the extract at 25 °C in dried form for compound was 989 days with activation energy 129.86 kJ·mol , and for it was 248 days with activation energy 110.57 kJ·mol , while in the extract solution, the predicted shelf-life of compounds - was 189, 13 and 75 days with activation energies 86.83, 51.49 and 65.28 kJ·mol , respectively. In addition, the pH-rate profiles of - indicated that they were stable in neutral to acidic environments.