Chemical Composition and Antimicrobial Activity of Essential Oil from Phytolacca dodecandra Collected in Ethiopia

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 2; p. 342
• Main Authors: Matebie, Wondwosen Abebe, Zhang, Wanchang, Xie, Guangbo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 18.01.2019; MDPI
• Subjects: Acids; Aldehydes; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; Bacteria - drug effects; Benzaldehyde; Biodiversity; Candida albicans - drug effects; Chemical composition; Chromatography; Communication; Distillation; essential oil; Essential oils; Ethiopia; Gas chromatography; Gender; Headspace; Herbal medicine; HS-SPME; Ketones; Mass spectrometry; Mass spectroscopy; Microbial Sensitivity Tests; Oils & fats; Oils, Volatile - chemistry; Oils, Volatile - pharmacology; Palmitic acid; Phytol; Phytolacca dodecandra; Phytolacca dodecandra - chemistry; Rabies; Solid phase methods; Solid phases; Steam distillation; Tropical diseases; Ethiopia; Lake Tana; United States > US; Addis Ababa Ethiopia; antimicrobial activity; essential oil; HS-SPME; Phytolacca dodecandra; chemical composition
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules24020342

The essential oil from , a traditional herb of Ethiopia, has been studied, including the chemical composition and antimicrobial activity. The difference between four samples (P-1⁻P-4), which differed in gender or location, has also been analyzed. The essential oils were obtained by steam distillation, while the aromas were extracted by head space solid-phase microextraction (HS-SPME) and both were analyzed by gas chromatography- mass spectrometry (GC-MS). The oils' antimicrobial activities were evaluated by the microdilution method against , , and . Ninety one components, representing 88.37 to 94.01% of the aromas, were identified. The compositions of the aromas of four samples are mainly dominated by aldehydes and ketones: 2-nonanone (1.80⁻30.80%), benzaldehyde (4.99⁻25.99%), and sulcatone (2.34⁻5.87%). Sixty components representing 64.61 to 69.64% of the oils were identified, and phytone (3.04⁻21.23%), phytol (4.11⁻26.29%) and palmitic acid (1.49⁻23.87%) are the major compounds. No obvious antimicrobial activity was observed for all the four essential oils.