Primary renal sclerosing epithelioid fibrosarcoma with metastasis to lung after 17 years

A 54-year-old female with a history of hepatitis C, right renal tumor post nephrectomy and benign uterus tumor post total hysterectomy was admitted to our hospital due to left lower lobe lung nodule. [...]we found that both lung and kidney specimens have strong MUC-4 expression (Figures 1A and 1B),...

Full description

Saved in:
Bibliographic Details
Published inThe Kaohsiung journal of medical sciences Vol. 38; no. 2; pp. 174 - 175
Main Authors Tsai, Dong‐Lin, Lee, Jui‐Ying, Lin, Chia‐Jung, Su, Yue‐Chiu
Format Journal Article
LanguageEnglish
Published BP, Asia Wiley Publishing Asia Pty Ltd 01.02.2022
John Wiley & Sons, Inc
Wiley
Subjects
Conflicts of interest
Female
Fibrosarcoma
Fibrosarcoma - secondary
Hepatitis C
Humans
Kidney Neoplasms - pathology
Lung Neoplasms - secondary
Metastasis
Middle Aged
Sarcoma
Thoracic surgery
Time Factors
Online AccessGet full text

Cover

More Information
Summary:A 54-year-old female with a history of hepatitis C, right renal tumor post nephrectomy and benign uterus tumor post total hysterectomy was admitted to our hospital due to left lower lobe lung nodule. [...]we found that both lung and kidney specimens have strong MUC-4 expression (Figures 1A and 1B), and bear EWSR1 gene break apart confirmed by FISH. Compare the specimen of kidney in 1998 and lung in 2015, both showed the same stain pattern and morphology Sclerosing epithelioid fibrosarcoma(SEF) is a low-grade variant of fibrosarcoma, which was first published by Meis-Kindblom in 1995, 1 and was recognized by WHO classification of soft tissue tumors since 2002. According to the currently published literature, it has wide age range from 17 to 61, typically occurring in middle aged adults. 3 And the mostly attacked locations are lower extremities, trunk, upper extremities, head and neck, and visceral organs.
ISSN:1607-551X
2410-8650
DOI:10.1002/kjm2.12458