Rapid Detection of Staphylococcus aureus and Methicillin-Resistant S. aureus (MRSA) in Wound Specimens and Blood Cultures: Multicenter Preclinical Evaluation of the Cepheid Xpert MRSA/SA Skin and Soft Tissue and Blood Culture Assays

• Published in: Journal of Clinical Microbiology Vol. 47; no. 3; pp. 823 - 826
• Main Authors: Wolk, D.M, Struelens, M.J, Pancholi, P, Davis, T, Della-Latta, P, Fuller, D, Picton, E, Dickenson, R, Denis, O, Johnson, D, Chapin, K
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.2009; American Society for Microbiology (ASM)
• Subjects: Bacteriological Techniques - methods; Bacteriology; Biological and medical sciences; Blood - microbiology; Fundamental and applied biological sciences. Psychology; Humans; Microbiology; Miscellaneous; Sensitivity and Specificity; Staphylococcal Infections - diagnosis; Staphylococcus aureus; Staphylococcus aureus - isolation & purification; Wounds and Injuries - microbiology; Microbiology; Tissue culture; Bacteria; Micrococcales; Micrococcaceae; Soft tissue; Skin; Detection; Blood culture; Wound; Staphylococcus aureus
• ISSN: 0095-1137; 1098-660X
• DOI: 10.1128/JCM.01884-08

A multicenter preclinical evaluation was conducted to evaluate the performance of two Cepheid Xpert assays for detection of methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus. Sensitivity was 97.1% and 98.3% for MRSA in wound and blood culture specimens, respectively. Sensitivity was 100% for S. aureus from both specimen types.