Pulmonary embolism after lung resection: diagnosis and treatment

Pulmonary embolism after lung resection (PEALR) has a high mortality rate, and it is one of the most severe complications after lung resection. Early diagnosis and treatment are essential for PEALR. Here we present 3 cases of severe PEALR. In these cases, transthoracic Doppler echocardiography was u...

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Published inThe Annals of thoracic surgery Vol. 76; no. 2; pp. 599 - 601
Main Authors Kameyama, Kotaro, Huang, Cheng-long, Liu, Dage, Okamoto, Taku, Hayashi, Eiichi, Yamamoto, Yasumichi, Yokomise, Hiroyasu
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.08.2003
Elsevier Science
Subjects
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Aged
Biological and medical sciences
Biopsy, Needle
Combined Modality Therapy - methods
Female
Follow-Up Studies
Heparin - therapeutic use
Humans
Infusions, Intravenous
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Male
Medical sciences
Middle Aged
Neoplasm Staging
Pneumonectomy - adverse effects
Pneumonectomy - methods
Pulmonary Embolism - diagnosis
Pulmonary Embolism - etiology
Pulmonary Embolism - therapy
Respiration, Artificial
Risk Assessment
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the respiratory system
Treatment Outcome
11
Human
Echocardiography
Serine endopeptidases
Pathophysiology
Respiratory disease
Enzyme
Treatment efficiency
Cardiovascular disease
Exploration
Surgical resection
Bronchopulmonary
t-Plasminogen activator
Vascular disease
Pulmonary embolism
Peptidases
Chemotherapy
Treatment
Hydrolases
Complication
Severity score
Diagnosis
Recombinant protein
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Summary:Pulmonary embolism after lung resection (PEALR) has a high mortality rate, and it is one of the most severe complications after lung resection. Early diagnosis and treatment are essential for PEALR. Here we present 3 cases of severe PEALR. In these cases, transthoracic Doppler echocardiography was useful for confirming the diagnosis of PEALR. Thrombolysis with recombinant tissue plasminogen activator (r-tPA) was used to treat the embolism, and these patients were subsequently discharged. Thus echocardiography may become a primary procedure to confirm the diagnosis of severe PEALR, and thrombolysis with second-generation r-tPA may be the preferred choice for treatment.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0003-4975
1552-6259
DOI:10.1016/S0003-4975(03)00005-5