Training response inhibition to food is associated with weight loss and reduced energy intake

• Published in: Appetite Vol. 95; pp. 17 - 28
• Main Authors: Lawrence, Natalia S., O'Sullivan, Jamie, Parslow, David, Javaid, Mahmood, Adams, Rachel C., Chambers, Christopher D., Kos, Katarina, Verbruggen, Frederick
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2015; Academic Press
• Subjects: Adult; Aged; Behavior Therapy - methods; Cognitive training; Diet Records; Disinhibition; Double-Blind Method; Energy Intake; Feeding Behavior - psychology; Female; Food liking; Food Preferences - psychology; Humans; Inhibition, Psychological; Male; Middle Aged; Obesity - diet therapy; Obesity - psychology; Overweight - diet therapy; Overweight - psychology; Research Report; Response inhibition; Snacks - psychology; Weight Loss; Young Adult; Energy intake; Disinhibition; Food liking; Response inhibition; Cognitive training; Weight loss
• ISSN: 0195-6663; 1095-8304
• DOI: 10.1016/j.appet.2015.06.009

The majority of adults in the UK and US are overweight or obese due to multiple factors including excess energy intake. Training people to inhibit simple motor responses (key presses) to high-energy density food pictures reduces intake in laboratory studies. We examined whether online response inhibition training reduced real-world food consumption and weight in a community sample of adults who were predominantly overweight or obese (N = 83). Participants were allocated in a randomised, double-blind design to receive four 10-min sessions of either active or control go/no-go training in which either high-energy density snack foods (active) or non-food stimuli (control) were associated with no-go signals. Participants' weight, energy intake (calculated from 24-h food diaries), daily snacking frequency and subjective food evaluations were measured for one week pre- and post-intervention. Participants also provided self-reported weight and monthly snacking frequency at pre-intervention screening, and one month and six months after completing the study. Participants in the active relative to control condition showed significant weight loss, reductions in daily energy intake and a reduction in rated liking of high-energy density (no-go) foods from the pre-to post-intervention week. There were no changes in self-reported daily snacking frequency. At longer-term follow-up, the active group showed significant reductions in self-reported weight at six months, whilst both groups reported significantly less snacking at one- and six-months. Excellent rates of adherence (97%) and positive feedback about the training suggest that this intervention is acceptable and has the potential to improve public health by reducing energy intake and overweight. [Display omitted] •We examine whether response inhibition training alters real-world eating behaviour.•Food no-go training (active) reduces energy intake, weight and food liking.•Non-food no-go training (control) has no effect pre-to post-intervention.•Both groups show reduced snacking at one and six-month follow-ups.•Active training is associated with self-reported weight loss at six-months.