Chemistry and biological activities of terpenoids from copaiba (Copaifera spp.) oleoresins

Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane sk...

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Published inMolecules Vol. 17; no. 4; pp. 3866 - 3889
Main Authors Leandro, Lidiam Maia, Vargas, Fabiano de Sousa, Barbosa, Paula Cristina Souza, Neves, Jamilly Kelly Oliveira, da Silva, José Alexsandro, da Veiga-Junior, Valdir Florêncio
Format Journal Article Book Review
LanguageEnglish
Published Switzerland MDPI AG 30.03.2012
MDPI
Subjects
Animals
copaiba oil
diterpenes
Fabaceae - chemistry
Humans
oleoresin
pharmacological activities
Plant Extracts - chemistry
Plant Extracts - pharmacology
Review
sesquiterpenes
Terpenes - chemistry
Terpenes - pharmacology
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Summary:Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules17043866