Comparison of Percutaneous Coronary Intervention With Bare-Metal and Drug-Eluting Stents for Cardiac Allograft Vasculopathy

• Published in: JACC. Cardiovascular interventions Vol. 1; no. 6; pp. 710 - 715
• Main Authors: Lee, Michael S., MD, Kobashigawa, Jon, MD, Tobis, Jonathan, MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2008
• Subjects: Angioplasty, Balloon, Coronary - adverse effects; Angioplasty, Balloon, Coronary - instrumentation; cardiac transplantation; Cardiovascular; Coronary Angiography; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - etiology; Coronary Stenosis - mortality; Coronary Stenosis - therapy; drug-eluting stent; Drug-Eluting Stents; Female; Graft Occlusion, Vascular - diagnostic imaging; Graft Occlusion, Vascular - etiology; Graft Occlusion, Vascular - mortality; Graft Occlusion, Vascular - therapy; Graft Survival; Heart Transplantation - adverse effects; Heart Transplantation - mortality; Humans; Los Angeles; Male; Metals; percutaneous coronary intervention; Prosthesis Design; Retrospective Studies; Severity of Illness Index; Stents; Thrombosis - etiology; Thrombosis - prevention & control; Time Factors; Transplantation, Homologous; Treatment Outcome; cardiac allograft vasculopathy; percutaneous coronary intervention; bare-metal stent(s); drug-eluting stent; DES; cardiac transplantation; orthotopic heart transplantation; PCI; BMS; CAV; OHT; drug-eluting stent(s)
• ISSN: 1936-8798; 1876-7605
• DOI: 10.1016/j.jcin.2008.10.001

Comparison of Percutaneous Coronary Intervention With Bare-Metal and Drug-Eluting Stents for Cardiac Allograft Vasculopathy Michael S. Lee, Jon Kobashigawa, Jonathan Tobis Cardiac allograft vasculopathy (CAV) is a rapidly progressive form of atherosclerosis and is one of the main limitations to long-term survival after orthotopic heart transplantation. Data on 82 consecutive patients with CAV who underwent stenting with bare-metal stents (BMS) and drug-eluting stents (DES) were retrospectively analyzed. When compared with BMS, stenting with DES was safe, reduced the rate of angiographic restenosis, and was associated with less late lumen loss in patients with CAV. No angiographic stent thrombosis was observed with DES.