Lectin microarray analysis of isolated polysaccharides from Sasa veitchii

We report lectin microarray profile of the polysaccharide fraction derived from Sasa veitchii leaf that exhibits anti-influenza activity. This fraction showed higher reactivities with lectins known as binders to oligo-mannose, fucose, or galactose. Our findings along with previously reported monosac...

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Published inBioscience, biotechnology, and biochemistry Vol. 81; no. 9; pp. 1687 - 1689
Main Authors Yagi, Hirokazu, Tateno, Hiroaki, Hayashi, Kyoko, Hayashi, Toshimitsu, Takahashi, Katsuhiko, Hirabayashi, Jun, Kato, Koichi, Tsuboi, Masamichi
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 02.09.2017
Oxford University Press
Subjects
anti-influenza virus activity
Antiviral Agents - metabolism
lectin microarray
Lectins - metabolism
polysaccharides
Polysaccharides - metabolism
Protein Array Analysis
Sasa - chemistry
Sasa veitchii
polysaccharides
lectin microarray
anti-influenza virus activity
Sasa veitchii
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Summary:We report lectin microarray profile of the polysaccharide fraction derived from Sasa veitchii leaf that exhibits anti-influenza activity. This fraction showed higher reactivities with lectins known as binders to oligo-mannose, fucose, or galactose. Our findings along with previously reported monosaccharide components suggest that the polysaccharide can be cross-reactive with cell surface receptors involved in immune system, thereby exerting anti-influenza activity.
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ISSN:0916-8451
1347-6947
DOI:10.1080/09168451.2017.1340089