Morphogen gradient interpretation
A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an embryo can determine the location, differentiation and fate of many surrounding cells. The value of this idea has been clear for over half a c...
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Published in | Nature (London) Vol. 413; no. 6858; pp. 797 - 803 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
England
Nature Publishing Group
25.10.2001
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Subjects | |
Online Access | Get full text |
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Abstract | A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an embryo can determine the location, differentiation and fate of many surrounding cells. The value of this idea has been clear for over half a century, but only recently have experimental systems and methods of analysis progressed to the point where we begin to understand how a cell can sense and respond to tiny changes in minute concentrations of extracellular signalling factors. |
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AbstractList | A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an embryo can determine the location, differentiation and fate of many surrounding cells. The value of this idea has been clear for over half a century, but only recently have experimental systems and methods of analysis progressed to the point where we begin to understand how a cell can sense and respond to tiny changes in minute concentrations of extracellular signalling factors. |
Audience | Academic |
Author | Bourillot, P.-Y Gurdon, J. B |
Author_xml | – sequence: 1 givenname: J. B surname: Gurdon fullname: Gurdon, J. B – sequence: 2 givenname: P.-Y surname: Bourillot fullname: Bourillot, P.-Y |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/11677596$$D View this record in MEDLINE/PubMed |
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Snippet | A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an... |
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SubjectTerms | Animals Cell Differentiation - physiology Cells Cellular biology Chemotactic Factors - physiology Drosophila Drosophila - embryology Embryonic Induction Embryos Emissions Gene Expression Regulation, Developmental Molecules Morphogenesis - genetics Morphogenesis - physiology Signal Transduction Wings, Animal - embryology |
Title | Morphogen gradient interpretation |
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