Synthesis of lactose-containing glycopolymer-grafted silica gel particles

• Published in: Journal of applied polymer science Vol. 116; no. 3; pp. 1611 - 1616
• Main Authors: Guo, Tian-Ying, Liu, Ping, Xia, Yong-Qing, Song, Mou-Dao
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 05.05.2010; Wiley
• Subjects: Applied sciences; chromatographic properties; Chromatography; Exact sciences and technology; glycopolymer; graft polymerization; Grafting; Initiators; Organic polymers; Physicochemistry of polymers; Polymerization; Polymers with particular properties; Preparation, kinetics, thermodynamics, mechanism and catalysts; Reproduction; Separation; Silica gel; Synthesis; Surface reaction; Separation capacity; HPLC chromatography; Experimental study; Flavonoid; Silica; Lateral group; Free radical polymerization; Polyphenol; Acrylate polymer; Preparation; Quercetin; Silica gel; Glycoside; chromatographic properties; glycopolymer; graft polymerization; Stationary phase; Graft polymers
• ISSN: 0021-8995; 1097-4628; 1097-4628
• DOI: 10.1002/app.31525

The surface free-radical graft polymerization of 2-O-meth-acryloyloxyethoxyl-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside onto silica gel particles has been carried out with azobis (isobutyronitrile) as initiator. The grafting reaction conditions and the glycopolymer-grafted silica gel particles have been investigated in detail. Chromatographic experiments have been attempted on glycopolymer-modified silica gel particles as a stationary phase under normal phase conditions, and it was found that a certain separation effect of the quercetin and its derivant isorhamnetin was achieved.