A 20-channel magnetoencephalography system based on optically pumped magnetometers

• Published in: Physics in medicine & biology Vol. 62; no. 23; pp. 8909 - 8923
• Main Authors: Borna, Amir, Carter, Tony R, Goldberg, Josh D, Colombo, Anthony P, Jau, Yuan-Yu, Berry, Christopher, McKay, Jim, Stephen, Julia, Weisend, Michael, Schwindt, Peter D D
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 10.11.2017
• Subjects: 60 APPLIED LIFE SCIENCES; Adult; auditory evoked magnetic field (AEF); Brain - physiology; CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; diffractive optical element (DOE); Humans; Magnetic Fields; magnetoencephalography; Magnetoencephalography - instrumentation; Magnetometry - instrumentation; Male; Optical Phenomena; optically pumped magnetometer (OPM); OTHER INSTRUMENTATION; somatosensory evoked magnetic field (SEF); spin-exchange relaxation-free (SERF); superconducting quantum interference device (SQUID)
• ISSN: 0031-9155; 1361-6560; 1361-6560
• DOI: 10.1088/1361-6560/aa93d1

We describe a multichannel magnetoencephalography (MEG) system that uses optically pumped magnetometers (OPMs) to sense the magnetic fields of the human brain. The system consists of an array of 20 OPM channels conforming to the human subject's head, a person-sized magnetic shield containing the array and the human subject, a laser system to drive the OPM array, and various control and data acquisition systems. We conducted two MEG experiments: auditory evoked magnetic field and somatosensory evoked magnetic field, on three healthy male subjects, using both our OPM array and a 306-channel Elekta-Neuromag superconducting quantum interference device (SQUID) MEG system. The described OPM array measures the tangential components of the magnetic field as opposed to the radial component measured by most SQUID-based MEG systems. Herein, we compare the results of the OPM- and SQUID-based MEG systems on the auditory and somatosensory data recorded in the same individuals on both systems.