The experiences of women with breast cancer who undergo fertility preservation

• Published in: Human reproduction open Vol. 2021; no. 2; p. hoab018
• Main Authors: Dahhan, T, van der Veen, F, Bos, A M E, Goddijn, M, Dancet, E A F
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.01.2021
• Subjects: Beliefs, opinions and attitudes; Breast cancer; Cancer patients; Care and treatment; Complications and side effects; Infertility, Female; Original; Psychological aspects; Risk factors; Netherlands; assisted reproduction; gonadotrophins; psychology; female infertility; vitrification; ovarian stimulation; qualitative research; reproductive decision making; cryopreservation
• ISSN: 2399-3529; 2399-3529
• DOI: 10.1093/hropen/hoab018

Abstract STUDY QUESTION How do women, who have just been diagnosed with breast cancer, experience oocyte or embryo banking? SUMMARY ANSWER Fertility preservation was a challenging yet welcome way to take action when confronted with breast cancer. WHAT IS KNOWN ALREADY Fertility preservation for women with breast cancer is a way to safeguard future chances of having children. Women who have just been diagnosed with breast cancer report stress, as do women who have to undergo IVF treatment. How women experience the collision of these two stressfull events, has not yet been studied. STUDY DESIGN, SIZE, DURATION We performed a multicenter qualitative study with a phenomenological approach including 21 women between March and July 2014. Women were recruited from two university-based fertility clinics. PARTICIPANTS/MATERIALS, SETTING, METHODS Women with breast cancer who banked oocytes or embryos 1–15 months before study participation were eligible. We conducted in-depth, face-to-face interviews with 21 women, which was sufficient to reach data saturation. MAIN RESULTS AND THE ROLE OF CHANCE The 21 women interviewed had a mean age of 32 years. Analysis of the 21 interviews revealed three main experiences: the burden of fertility preservation, the new identity of a fertility patient and coping with breast cancer through fertility preservation. LIMITATIONS, REASONS FOR CAUTION Interviewing women after, rather than during, fertility preservation might have induced recall bias. Translation of quotes was not carried out by a certified translator. WIDER IMPLICATIONS OF THE FINDINGS The insights gained from this study of the experiences of women undergoing fertility preservation while being newly diagnosed with breast cancer could be used as a starting point for adapting the routine psychosocial care provided by fertility clinic staff. Future studies are necessary to investigate whether adapting routine psychosocial care improves women’s wellbeing. STUDY FUNDING/COMPETING INTEREST(S) None of the authors in this study declare potential conflicts of interest. The study was funded by the Center of Reproductive Medicine of the Academic Medical Center.