Relationship between Antioxidant Properties and Chemical Composition of Abutilon Indicum Linn

• Published in: Indian journal of pharmaceutical sciences Vol. 74; no. 2; pp. 163 - 167
• Main Authors: Srividya, A R, Dhanabal, S P, Jeevitha, S, Varthan, V J Vishnu, Kumar, R Rajesh
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.03.2012; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Acids; Antioxidants; Free radicals; Hydrogen peroxide; Phytochemicals; Phytochemistry; Properties; Short Communications; India; Mumbai India; antioxidant; nitric oxide; DPPH; nydrogen peroxide; total antioxidant capacity; Abutilon indicum linn; deoxyribose; lipid peroxidation; ABTS
• ISSN: 0250-474X; 1998-3743
• DOI: 10.4103/0250-474X.103854

Aim of this paper is to find out the relationship between antioxidant activity of Abutilon indicum Linn and their phytochemical composition especially phenols and flavonols. Successive extractions were carried out for the Abutilon indicum plant with petroleum ether, chloroform, ethyl acetate, n-butanol, ethanol and water. All these extracts were evaluated for their antioxidant activities. Their antioxidant activities were correlated with their total phenol and flavonol content present in the plant. Ethyl acetate showed maximum free radical scavenging activity. IC(50) value for various antioxidant methods for all extract showed no significance with total antioxidant capacity except IC(50) value of LPO (r(2) = 0.7273). Correlation between total antioxidant capacity and total phenolic content was not significant with r(2) = 0.2554, P<0.3065. Total antioxidant capacity and total flavonol content showed similar correlation with r(2) = 0.2554, P<0.0962.