Squamous cell carcinoma and dental implants: A systematic review of case reports

• Published in: Journal of pharmacy & bioallied science Vol. 7; no. Suppl 2; pp. S378 - S380
• Main Authors: Jeelani, S, Rajkumar, E, Mary, G Geena, Khan, Parvez Ahmad, Gopal, Harish, Roy, Soumya, Maheswaran, T, Anand, B
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.08.2015; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Biopsy; Cervical cancer; Complications and side effects; Cytokines; Dental Science - Review; Implant dentures; Inflammation; Mouth cancer; Oral cancer; Rehabilitation; Risk factors; Squamous cell carcinoma; Tumor necrosis factor-TNF; Vascular endothelial growth factor; Chronic inflammation; dental implants; squamous cell carcinoma
• ISSN: 0976-4879; 0975-7406; 0975-7406
• DOI: 10.4103/0975-7406.163457

Cancer is one of the leading causes of death world-wide. Apart from the most common etiopathological factors related to cancer, at times very rare causes such as irritant or foreign body induced carcinogenesis is not to be overlooked. To systematically review case reports concerned with the association between dental implants and oral squamous cell carcinoma. A Medline (PubMed), Cochrane database, and Google Scholar search was conducted of dental article published in English related to case reports concerned with oral squamous cell carcinoma occurring around dental implants from 2000 to 2014. Twenty articles were retrieved, which included 20 rare case reports which were systematically reviewed and the results were obtained pertaining to age, clinical symptoms, habits, previous history of cancer, potentially malignant disorders, systemic illness, and local factors. It is imperative to identify promptly persisting inflammation associated with implants. Since malignancy may disguise as periimplantitis, especially in patients who are at risk with contributing prominent predisposing factors.