Inclusion and release of proteins from polysaccharide-based polyion complexes

The notion of a polyelectrolyte complex is well established for the complexation of two polymers one anionic, the other cationic. Electronic microscopy studies have shown the formation of a fibrilar structure. A method for the preparation of polyionic hydrogels from the complexation of chitosan and...

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Bibliographic Details
Published inAdvanced drug delivery reviews Vol. 31; no. 3; pp. 223 - 246
Main Authors Dumitriu, Severian, Chornet, Esteban
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 04.05.1998
Subjects
Catalyst activity
Chitosan
Complexation
Electron microscopy
Enzyme immobilization
Hydrogels
Molecular structure
Polyelectrolyte complex
Polyelectrolytes
Polysaccharides
Proteins
Xanthan
Xanthan
Complexation
Chitosan
Polyelectrolyte complex
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Summary:The notion of a polyelectrolyte complex is well established for the complexation of two polymers one anionic, the other cationic. Electronic microscopy studies have shown the formation of a fibrilar structure. A method for the preparation of polyionic hydrogels from the complexation of chitosan and xanthan is reported. Electronic microscopy studies have shown the formation of a fibrilar structure. Stable hydrogels have been used to immobilize xylanase, lipase and protease. The immobilized xylanase and lipase activity was significantly higher than that of the free enzyme.
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ISSN:0169-409X
1872-8294
DOI:10.1016/S0169-409X(97)00120-8