Non-Visual Photoreception: Sensing Light without Sight

Recent work in blind human subjects has confirmed the presence of a non-visual ocular photoreceptive mechanism similar to that described in blind mice. This system appears to subserve circadian photic entrainment, the pupillary light response, and a number of other aspects of neurophysiology and beh...

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Bibliographic Details
Published inCurrent biology Vol. 18; no. 1; pp. R38 - R39
Main Author Van Gelder, Russell N.
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 08.01.2008
Subjects
Blindness - physiopathology
Circadian Rhythm
Humans
Light
Light Signal Transduction - physiology
Retinal Ganglion Cells - physiology
Rod Opsins - physiology
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Summary:Recent work in blind human subjects has confirmed the presence of a non-visual ocular photoreceptive mechanism similar to that described in blind mice. This system appears to subserve circadian photic entrainment, the pupillary light response, and a number of other aspects of neurophysiology and behavior.
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ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2007.11.027