Occupational Exposure and Thoracic Malignancies, Is There a Relationship ?

• Published in: Journal of occupational health Vol. 55; no. 4; pp. 301 - 306
• Main Authors: Baser, Sevin, Duzce, Ozlem, Evyapan, Fatma, Akdag, Beyza, Ozkurt, Sibel, Kiter, Goksel
• Format: Journal Article
• Language: English
• Published: Australia John Wiley & Sons, Inc 01.07.2013
• Subjects: Aged; Agricultural land; Agriculture; Asbestos; Case-Control Studies; Confidence Intervals; Dust; Dust - analysis; Exposure; Female; Humans; Inorganic dust; Lung cancer; Male; Middle Aged; Occupational exposure; Occupational Exposure - adverse effects; Occupational Exposure - analysis; Occupational health; Odds Ratio; Organic dust; Surveys and Questionnaires; Thoracic Neoplasms - epidemiology; Thoracic Neoplasms - etiology; Turkey - epidemiology; Turkey
• ISSN: 1348-9585; 1341-9145; 1348-9585
• DOI: 10.1539/joh.13-0097-FS

Occupational Exposure and Thoracic Malignancies, Is There a Relationship ?: Sevin BASER, et al. Department of Pulmonary Medicine, Pamukkale University Medical Faculty, Turkey—The aim of this study was to evaluate the effect of occupational exposure in the occurrence of lung cancer. Method Three‐hundred lung cancer cases diagnosed between September 1, 1999, and September 31, 2007, and 300 healthy controls were enrolled in this casecontrol study. Life‐long occupational history, gender, age, exposure to asbestos, comorbidities, and smoking status were collected. Results The mean age of the 300 lung cancer cases was 60.3 ± 9.9 year (91.7% male and 8.3% female), and the mean age of healthy control group was 60.4 ± 10.5 year (95.0% male and 5.0% female). The most frequent histological types were squamous (172, 57.3%), adeno (69, 23.1%), and small cell (37, 12.3%). There was an increased risk of lung cancer occurrence among agriculture workers (OR=1.89, 95% Cl=1.17−2.98) (p=0.009). Inorganic dust exposure (OR=1.81, 95% Cl=1.0−3.25) (p=0.049) and organic dust exposure (OR=1.89, 95% Cl=1.0−3.59) (p=0.05) were found to be related with high frequency of having lung cancer. Conclusion Workers who had occupational exposure to organic and inorganic dust, especially in the agricultural field, had higher risk of lung cancer occurrence when compared with office workers.