Expectations of the Physiological Responses Can Change the Somatosensory Experience for Acupuncture Stimulation

• Published in: Frontiers in neuroscience Vol. 13; p. 74
• Main Authors: Song, Hyun-Seo, Jung, Won-Mo, Lee, Ye-Seul, Yoo, Seung-Woo, Chae, Younbyoung
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 12.02.2019; Frontiers Media S.A
• Subjects: Acupuncture; biosignal; Blood flow; Brain research; Cognition & reasoning; de qi; Doppler effect; expectation; Experiments; Lasers; Mapping; Neuroscience; Pain; Perceptions; Perfusion; Peripheral blood; psychophysics; Studies; Tactile stimuli; South Korea; de qi; acupuncture; expectation; psychophysics; biosignal
• ISSN: 1662-4548; 1662-453X; 1662-453X
• DOI: 10.3389/fnins.2019.00074

Humans interpret sensory inputs based on actual stimuli and expectations of the stimuli. We investigated whether manipulating information related to the physiological response could change the somatosensory experience of acupuncture. Twenty-four participants received tactile stimulations with a von Frey filament on the left arm. Participants were informed that they would receive acupuncture stimulations at different angles while they were presented with changes in their peripheral blood flow (PBF) measured with Laser Doppler perfusion imaging. However, in reality, they were observing premade pseudo-biosignal images (six sessions: one circular, two rectangular elongated, two diagonally elongated, and one cross-fixation [control] shape). After each session, the participants reported the intensity and location of the sensations perceived on their arm using a bodily sensation mapping tool. The spatial patterns of the somatic sensations were visualized using statistical parametric mapping. The F1 score was calculated to measure the similarity between the presented pseudo-biosignals and reported response images. The spatial configurations of the presented pseudo-biosignal images and response images were similar. The rectangular elongated pseudo-biosignal shape had a significantly higher F1 score compared to the control. All tactile stimulations produced similar levels of enhanced PBF regardless of the pseudo-biosignal shape. The spatial configurations of somatic sensations changed according to the presented pseudo-biosignal shape, suggesting that expectations of the physiological response to acupuncture stimulation can influence the perceived somatic sensation.