Functional Integration Between the Two Brain Hemispheres: Evidence From the Homotopic Functional Connectivity Under Resting State

Functional integration among neural units is one of the fundamental principles in brain organization that could be examined using resting-state functional connectivity (rs-FC). Interhemispheric functional integration plays a critical role in human cognition. Homotopic functional connectivity (HoFC)...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in neuroscience Vol. 14; p. 932
Main Authors Jin, Xinhu, Liang, Xinyu, Gong, Gaolang
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Research Foundation 02.10.2020
Frontiers Media S.A
Subjects
Brain
Brain architecture
Brain mapping
Cerebral hemispheres
Cognition & reasoning
Cognitive ability
functional integration
Functional magnetic resonance imaging
Functional morphology
Hemispheric laterality
homotopic functional connectivity
Information processing
Integration
Investigations
left and right brain hemispheres
Medical imaging
Neural networks
Neuroimaging
Neuroscience
Neurosciences
resting-state functional connectivity
resting-state functional magnetic resonance imaging
Time series
resting-state functional magnetic resonance imaging
resting-state functional connectivity
homotopic functional connectivity
functional integration
left and right brain hemispheres
Online AccessGet full text

Cover

More Information
Summary:Functional integration among neural units is one of the fundamental principles in brain organization that could be examined using resting-state functional connectivity (rs-FC). Interhemispheric functional integration plays a critical role in human cognition. Homotopic functional connectivity (HoFC) under resting state provide an avenue to investigate functional integration between the two brain hemispheres, which can improve the present understanding of how interhemispheric interactions affect cognitive processing. In this review, we summarize the progress of HoFC studies under resting state and highlight how these findings have enhanced our understanding of interhemispheric functional organization of the human brain. Future studies are encouraged to address particular methodological issues and to further ascertain behavioral correlates, brain disease's modulation, task influence, and genetic basis of HoFC.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
This article was submitted to Brain Imaging Methods, a section of the journal Frontiers in Neuroscience
Edited by: Xin Di, New Jersey Institute of Technology, United States
These authors have contributed equally to this work
Reviewed by: Dapeng Liu, Johns Hopkins University, United States; Ye He, Indiana University, United States; Zhengjia Dai, Sun Yat-sen University, China
ISSN:1662-453X
1662-4548
1662-453X
DOI:10.3389/fnins.2020.00932