System of integrating biosignals during hemodialysis: the CONTINUAL (Continuous mOnitoriNg viTal sIgN dUring hemodiALysis) registry

• Published in: Kidney research and clinical practice Vol. 41; no. 3; pp. 363 - 371
• Main Authors: Kim, Seonmi, Yun, Donghwan, Kwon, Soonil, Lee, So-Ryoung, Kim, Kwangsoo, Kim, Yong Chul, Kim, Dong Ki, Oh, Kook-Hwan, Joo, Kwon Wook, Lee, Hyung-Chul, Jung, Chul-Woo, Kim, Yon Su, Han, Seung Seok
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Nephrology 01.05.2022; 대한신장학회
• Subjects: biosignal; cardiac arrhythmias; hypertension; hypotension; Original; renal dialysis; 내과학; Hypertension; Biosignal; Cardiac arrhythmias; Renal dialysis; Hypotension
• ISSN: 2211-9132; 2211-9140
• DOI: 10.23876/j.krcp.21.157

Appropriate monitoring of intradialytic biosignals is essential to minimize adverse outcomes because intradialytic hypotension and arrhythmia are associated with cardiovascular risk in hemodialysis patients. However, a continuous monitoring system for intradialytic biosignals has not yet been developed. This study investigated a cloud system that hosted a prospective, open-source registry to monitor and collect intradialytic biosignals, which was named the CONTINUAL (Continuous mOnitoriNg viTal sIgN dUring hemodiALysis) registry. This registry was based on real-time multimodal data acquisition, such as blood pressure, heart rate, electrocardiogram, and photoplethysmogram results. We analyzed session information from this system for the initial 8 months, including data for some cases with hemodynamic complications such as intradialytic hypotension and arrhythmia. This biosignal registry provides valuable data that can be applied to conduct epidemiological surveys on hemodynamic complications during hemodialysis and develop artificial intelligence models that predict biosignal changes which can improve patient outcomes.