Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs

Platelet-rich plasma (PRP) is known to play a crucial role in skin wound healing, in both Human and Veterinary Medicine. Remarkably, until now, no studies have reported PRP treatment in subacute full-thickness skin wounds of the dog. The aim of this study was to evaluate the effects of two consecuti...

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Published inFrontiers in veterinary science Vol. 7; p. 575449
Main Authors Iacopetti, Ilaria, Patruno, Marco, Melotti, Luca, Martinello, Tiziana, Bedin, Silvia, Badon, Tamara, Righetto, Edoardo Maria, Perazzi, Anna
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 26.10.2020
Subjects
autologous platelet-rich plasma
cutaneous wound healing
dog
regenerative medicine
subacute wounds
Veterinary Science
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Summary:Platelet-rich plasma (PRP) is known to play a crucial role in skin wound healing, in both Human and Veterinary Medicine. Remarkably, until now, no studies have reported PRP treatment in subacute full-thickness skin wounds of the dog. The aim of this study was to evaluate the effects of two consecutive applications of autologous PRP, with the second application after 15 days, in 6 dogs showing large subacute skin wounds. The percentage of contraction, re-epithelialization and healing in all treated patients indicated that no complications or side effects, associated with consecutive PRP treatments, occurred in any patient and all wounds achieved complete closure and re-epithelialization. Our results suggest a positive effect of repeated autologous topical PRP treatments in large cutaneous subacute wounds of different etiology. Therefore, this PRP treatment could represent a simple, cost-effective, and valid alternative to promote healing processes in subacute large wounds cases in dogs.
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Edited by: Roberta Perego, University of Milan, Italy
This article was submitted to Comparative and Clinical Medicine, a section of the journal Frontiers in Veterinary Science
Reviewed by: Adolfo Maria Tambella, University of Camerino, Italy; Dilip Kumar Garikipati, Cleveland Clinic, United States
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2020.575449