ReDO_DB: the repurposing drugs in oncology database

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-bas...

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Published inEcancermedicalscience Vol. 12; p. 886
Main Authors Pantziarka, Pan, Verbaanderd, Ciska, Sukhatme, Vidula, Capistrano, Rica, Crispino, Sergio, Gyawali, Bishal, Rooman, Ilse, Van Nuffel, An MT, Meheus, Lydie, Sukhatme, Vikas P, Bouche, Gauthier
Format Journal Article
LanguageEnglish
Published England Cancer Intelligence 06.12.2018
Subjects
Cancer
Candidates
Clinical trials
Costs
Drug development
Drug therapy
Licenses
Licensing
Oncology
Pharmaceutical industry
Belgium
United States > US
ReDO project
online database
repositioning
drug repurposing
cancer drugs
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ISSN1754-6605
1754-6605
DOI10.3332/ecancer.2018.886

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Summary:Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).
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ISSN:1754-6605
1754-6605
DOI:10.3332/ecancer.2018.886