Technical Considerations for Lung Transplantation in Kartagener’s Syndrome

Kartagener’s syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung tr...

Full description

Saved in:
Bibliographic Details
Published inThe Annals of thoracic surgery Vol. 107; no. 5; pp. e337 - e339
Main Authors Gauthier, Jason M., Takahashi, Tsuyoshi, Bierhals, Andrew J., Brody, Steven L., Hachem, Ramsey R., Witt, Chad A., Byers, Derek E., Yusen, Roger D., Trulock, Elbert P., Aguilar, Patrick R., Nava, Ruben G., Kozower, Benjamin D., Meyers, Bryan F., Patterson, G. Alexander, Kreisel, Daniel, Puri, Varun
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.05.2019
Subjects
Cardiopulmonary Bypass
Humans
Kartagener Syndrome - surgery
Lung Transplantation - methods
Male
Middle Aged
Online AccessGet full text

Cover

More Information
Summary:Kartagener’s syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. We report a case of bilateral lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener’s syndrome while describing important technical details of the operation.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0003-4975
1552-6259
DOI:10.1016/j.athoracsur.2018.08.095