Time-Perception Network and Default Mode Network Are Associated with Temporal Prediction in a Periodic Motion Task

• Published in: Frontiers in human neuroscience Vol. 10; p. 268
• Main Authors: Carvalho, Fabiana M, Chaim, Khallil T, Sanchez, Tiago A, de Araujo, Draulio B
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 02.06.2016; Frontiers Media S.A
• Subjects: Attention; Brain; Cerebellum; Cortex (cingulate); Cortex (parietal); Cortex (premotor); fMRI; Functional magnetic resonance imaging; Hemispheric laterality; Information processing; internal model; Motion detection; Neuroscience; Prefrontal cortex; Presupplementary motor area; System theory; Temporal cortex; temporal expectation; Temporal perception; Temporal Prediction; Violations; Brazil; fMRI; attention; temporal expectation; internal model; temporal prediction
• ISSN: 1662-5161; 1662-5161
• DOI: 10.3389/fnhum.2016.00268

The updating of prospective internal models is necessary to accurately predict future observations. Uncertainty-driven internal model updating has been studied using a variety of perceptual paradigms, and have revealed engagement of frontal and parietal areas. In a distinct literature, studies on temporal expectations have also characterized a time-perception network, which relies on temporal orienting of attention. However, the updating of prospective internal models is highly dependent on temporal attention, since temporal attention must be reoriented according to the current environmental demands. In this study, we used functional magnetic resonance imaging (fMRI) to evaluate to what extend the continuous manipulation of temporal prediction would recruit update-related areas and the time-perception network areas. We developed an exogenous temporal task that combines rhythm cueing and time-to-contact principles to generate implicit temporal expectation. Two patterns of motion were created: periodic (simple harmonic oscillation) and non-periodic (harmonic oscillation with variable acceleration). We found that non-periodic motion engaged the exogenous temporal orienting network, which includes the ventral premotor and inferior parietal cortices, and the cerebellum, as well as the presupplementary motor area, which has previously been implicated in internal model updating, and the motion-sensitive area MT+. Interestingly, we found a right-hemisphere preponderance suggesting the engagement of explicit timing mechanisms. We also show that the periodic motion condition, when compared to the non-periodic motion, activated a particular subset of the default-mode network (DMN) midline areas, including the left dorsomedial prefrontal cortex (DMPFC), anterior cingulate cortex (ACC), and bilateral posterior cingulate cortex/precuneus (PCC/PC). It suggests that the DMN plays a role in processing contextually expected information and supports recent evidence that the DMN may reflect the validation of prospective internal models and predictive control. Taken together, our findings suggest that continuous manipulation of temporal predictions engages representations of temporal prediction as well as task-independent updating of internal models.