Broiler responses to dietary 3,4,5-trihydroxybenzoic acid and oregano extracts under Eimeria challenge conditions

• Published in: Journal of animal science and technology Vol. 63; no. 6; pp. 1362 - 1375
• Main Authors: Yu, Myunghwan, Jeon, Jong Oh, Cho, Hyun Min, Hong, Jun Seon, Kim, Yu Bin, Nawarathne, Shan Randima, Wickramasuriya, Samiru Sudharaka, Yi, Young-Joo, Lee, Hans, Wan, Vannie, Ng, Noele Kai Jing, Tan, Chuan Hao, Heo, Jung Min
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Society of Animal Sciences and Technology 01.11.2021; 한국축산학회
• Subjects: 3,4,5-trihydroxybenzoic acid; broiler; coccidiosis; growth performance; oregano extract; 축산학; 3,4,5-Trihydroxybenzoic acid; Oregano extract; Coccidiosis; Broiler; Growth performance
• ISSN: 2672-0191; 2055-0391; 2093-6281
• DOI: 10.5187/jast.2021.e121

This study was conducted to evaluate the efficacy of a combination 3,4,5-trihydroxybenzoic acid (THB) and oregano extracts (i.e., Carvacrol and Thymol) at intake/dietary different levels on growth performance, intestinal health indicators, immune responses and fecal oocyst shedding in broiler chickens under challenged condition. A total of 336 one-day-old broilers were randomly assigned to one of six dietary treatments with seven replications per treatment. Dietary treatments were: i) Non-challenged bird without any dietary treatment (NCNT), ii) Challenged bird without any dietary treatment (CNT), iii) Challenged birds fed a THB diet (0.1 g/kg, THB), iv) Challenged birds fed a combination of THB and oregano extracts diet (0.1 g/kg, COM 100), and a gradual increase of combination of THB and oregano extracts likely v) 0.15 g/kg (COM 150), and 0.2 g/kg (COM 200). On day 14, all groups except for NCNT have orally challenged with a 10-fold dose of Livacox® T anticoccidial vaccine to trigger coccidiosis. The results indicated that -challenged broilers fed COM 100 and COM 200 diets increased ( < 0.05) body weight than CNT diet on day 35. Furthermore, birds fed COM 100 and COM 200 diets increased ( < 0.05) average daily gain compared to those fed CNT diets for the entire experimental period. There is no significant ( > 0.05) in average daily feed intake, feed efficiency between NCNT and birds fed with combined THB and oregano extracts for the entire experimental period. A combination of THB and oregano extract regardless of concentration levels or THB alone reduced ( < 0.05) lesion score in ileum compared to the CNT diet for 7 days post-infection (dpi). Birds fed COM 100 diet had lower ( < 0.05) intestinal lesion scores in jejunum and caeca on 7 dpi compared to those were in the CNT diet. No ( > 0.05) difference was observed in the oocysts per gram of feces count, intestinal morphology, carcass traits and blood cytokine concentration among the infected treatments. Collectively, we conclude that birds fed with a combination of THB and oregano extracts regardless of the ratios that were used demonstrated better recovery of health after the coccidial challenge than using only THB alone.