The Astrophysical Formation of Asymmetric Molecules and the Emergence of a Chiral Bias

• Published in: Life (Basel, Switzerland) Vol. 9; no. 1; p. 29
• Main Authors: Garcia, Adrien D, Meinert, Cornelia, Sugahara, Haruna, Jones, Nykola C, Hoffmann, Søren V, Meierhenrich, Uwe J
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 16.03.2019; MDPI
• Subjects: Amino acids; Anisotropy; Astrophysics; Asymmetry; Bias; Biomolecules; Carbonaceous meteorites; Chemical Sciences; chirality; Comets; Energy sources; Ice; interstellar; Interstellar matter; Light; Meteorites; or physical chemistry; Organophosphorus compounds; Polarized light; Radiation; Review; Sciences of the Universe; Solar system; Space missions; Spectrum analysis; Sugar; sugars; Symmetry; Theoretical and; meteorites; sugars; chirality; comets; interstellar; amino acids
• ISSN: 2075-1729; 2075-1729
• DOI: 10.3390/life9010029

The biomolecular homochirality in living organisms has been investigated for decades, but its origin remains poorly understood. It has been shown that circular polarized light (CPL) and other energy sources are capable of inducing small enantiomeric excesses ( s) in some primary biomolecules, such as amino acids or sugars. Since the first findings of amino acids in carbonaceous meteorites, a scenario in which essential chiral biomolecules originate in space and are delivered by celestial bodies has arisen. Numerous studies have thus focused on their detection, identification, and enantiomeric excess calculations in extraterrestrial matrices. In this review we summarize the discoveries in amino acids, sugars, and organophosphorus compounds in meteorites, comets, and laboratory-simulated interstellar ices. Based on available analytical data, we also discuss their interactions with CPL in the ultraviolet (UV) and vacuum ultraviolet (VUV) regions, their abiotic chiral or achiral synthesis, and their enantiomeric distribution. Without doubt, further laboratory investigations and upcoming space missions are required to shed more light on our potential extraterrestrial molecular origins.