Essential fatty acids and their trans geometrical isomers in powdered and liquid infant formulas sold in Canada

• Published in: Journal of pediatric gastroenterology and nutrition Vol. 25; no. 4; pp. 400 - 407
• Main Authors: Ratnayake, W.M.N, Chardigny, J.M, Wolff, R.L, Bayard, C.C, Sebedio, J.L, Martine, L
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Hagerstown, MD Lippincott-Raven Publishers 01.10.1997; Lippincott; Lippincott, Williams & Wilkins
• Subjects: ACIDE GRAS ESSENTIEL; ACIDOS GRASOS ESENCIALES; ALIMENT POUR NOURRISSON; ALIMENTOS PARA NINOS; alpha-Linolenic Acid - analysis; Biological and medical sciences; CANADA; Chromatography, Gas - methods; ESSENTIAL FATTY ACIDS; Fatty Acids, Essential - analysis; Fatty Acids, Essential - chemistry; Fatty Acids, Volatile - analysis; Fatty Acids, Volatile - chemistry; Human physiology applied to population studies and life conditions. Human ecophysiology; Humans; Infant; Infant Food - analysis; INFANT FOODS; Infant, Newborn; Isomerism; Life Sciences; Linoleic Acid - analysis; Medical sciences; Nutritional survey. Food supply and nutritional requirement; Oleic Acid - analysis; Canada; Human; Nutrition; Neonatology; Fatty acids; Essential; Feeding; Linoleic acid; Result; Humanized milk; Linolenic acid; Newborn; Oleic acid; Trans stereoisomer; Geometrical isomer; Chemical composition; PEDIATRIE
• ISSN: 0277-2116; 1536-4801
• DOI: 10.1097/00005176-199710000-00007

BACKGROUNDAnimal and human studies have suggested that trans fatty acids might alter some physiological functions and adversely affect the growth and essential fatty acid balance of infants. In this context it is important to know the fatty acid composition, including the levels of trans isomers of oleic, linoleic and α-linolenic acids in infant formulas. METHODSTen liquid and fourteen powdered formulas for term infants were purchased from retail stores in Canada. The fatty acid composition of each formula was determined by capillary gas-liquid chromatography. RESULTSAll the formulas met the mimimum content of 500 mg of linoleic acid/100 kcal formula (equivalent to 4.5% of energy) specified under current Canadian regulations. The formulas all met the minimum energy levels of 3% as linoleic acid and 0.7% as α-linolenic acid recommended recently by an ad hoc committee of Health Canada. However, in nine formulas, the proportion of linoleic acid was more than 20% of total fatty acids, and consequently, in five of them, the ratio of linoleic acid to α-linolenic acid exceeded the maximum ratio of 16:1 recommended by the ad hoc committee. Trans fatty acids were present in all the samples, and generally the liquid formulas displayed a higher total trans content (mean 1.9%, range 0.9-3.1%) than powdered formulas (mean 1.4%, range 0.6-2.5%). The amounts of trans isomers of linoleic and α-linolenic acids and the degree of isomerization of these fatty acids were also higher in liquid formulas than in powdered formulas. CONCLUSIONSA few of the Canadian infant formulas would provide one-third of α-linolenic acid as trans geometric isomers.