Spatial/temporal correlation of BOLD and optical intrinsic signals in humans

• Published in: Magnetic resonance in medicine Vol. 47; no. 4; pp. 766 - 776
• Main Authors: Pouratian, Nader, Sicotte, Nancy, Rex, David, Martin, Neil A., Becker, Donald, Cannestra, Andrew F., Toga, Arthur W.
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.04.2002; Williams & Wilkins
• Subjects: Biological and medical sciences; BOLD; Brain - physiology; Brain Mapping; electrocortical stimulation mapping; Electrophysiology; fMRI; Humans; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Medical sciences; Miscellaneous. Technology; optical imaging; Optics and Photonics; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Time Factors; Tongue - physiology; within-subject analysis; Space; Human; Correlation; Tongue; Oxygen; Stimulation; Mapping; Time; Motor control; Nuclear magnetic resonance imaging; Blood; Functional; Optical signal; Optical image; Dependence; Medical imagery; Technique; Localization; Comparative study

Comparing the BOLD signal with electrophysiological maps and other perfusion‐dependent signals, such as the optical intrinsic signal (OIS), within subjects should provide insight into the etiology of the BOLD signal. Tongue activations were compared in five human subjects using BOLD fMRI, 610‐nm OIS...