Breast tumors: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent

• Published in: Radiology Vol. 197; no. 3; p. 743
• Main Authors: Boetes, C, Mus, R D, Holland, R, Barentsz, J O, Strijk, S P, Wobbes, T, Hendriks, J H, Ruys, S H
• Format: Journal Article
• Language: English
• Published: United States 01.12.1995
• Subjects: Adult; Aged; Breast Neoplasms - diagnosis; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - pathology; Carcinoma - diagnosis; Carcinoma - diagnostic imaging; Carcinoma - pathology; Contrast Media; Drug Combinations; Female; Gadolinium; Gadolinium DTPA; Humans; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging - statistics & numerical data; Mammography - statistics & numerical data; Mastectomy; Meglumine; Middle Aged; Neoplasm Invasiveness; Organometallic Compounds; Pentetic Acid - analogs & derivatives; Preoperative Care; Sensitivity and Specificity; Ultrasonography, Mammary - statistics & numerical data
• ISSN: 0033-8419
• DOI: 10.1148/radiology.197.3.7480749

To evaluate the comparative accuracy of magnetic resonance (MR) imaging relative to mammography and ultrasonography (US) for assessing the extent of breast tumors. Histologic results and preoperative imaging findings (mammography, US, MR imaging) were analyzed regarding tumor size and multifocality of 61 tumors in 60 women undergoing mastectomy for carcinoma. In 10% of cases, the index tumor was not seen at mammography. With US, 15% of the index tumors were not recognized, while MR imaging missed 2% of the index tumors. On mammographic and US images, tumor size was underestimated significantly (P < .005), by 14% and 18%, respectively, while MR imaging showed no significant difference in size compared with that found in a pathologic evaluation. Mammography showed 31% of the additional invasive lesions, while US showed 38% and MR imaging showed 100%. MR imaging was the most accurate of the three preoperative imaging modalities in assessing the size and number of malignant lesions in the breast.