The Effect of Urban Air Pollution on Inflammation, Oxidative Stress, Coagulation, and Autonomic Dysfunction in Young Adults

• Published in: American journal of respiratory and critical care medicine Vol. 176; no. 4; pp. 370 - 376
• Main Authors: Chuang, Kai-Jen, Chan, Chang-Chuan, Su, Ta-Chen, Lee, Chung-Te, Tang, Chin-Sheng
• Format: Journal Article
• Language: English
• Published: New York, NY Am Thoracic Soc 15.08.2007; American Lung Association; American Thoracic Society
• Subjects: Adolescent; Adult; Adult and adolescent clinical studies; Air Pollutants - chemistry; Air pollution; Air Pollution - adverse effects; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Anxiety disorders. Neuroses; Biological and medical sciences; Biomarkers - blood; Blood Coagulation - physiology; Blood. Blood coagulation. Reticuloendothelial system; C-Reactive Protein - analysis; Cardiovascular disease; Cardiovascular system; College campuses; College students; Colleges & universities; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - blood; Environmental Monitoring; Enzymes; Female; Fibrinogen - analysis; Heart rate; Heart Rate - physiology; Human subjects; Humans; Inflammation; Inflammation - physiopathology; Intensive care medicine; Male; Medical sciences; Nitrogen dioxide; Outdoor air quality; Oxidative stress; Oxidative Stress - physiology; Particle Size; Pharmacology. Drug treatments; Plasma; Plasminogen Activator Inhibitor 1 - blood; Pollutants; Post-traumatic stress disorder; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Taiwan; Tissue Plasminogen Activator - blood; Urban Health; Urban Population; Young adults; Taiwan; Japan; Taiwan, Taipei; Human; Heart rate; Blood coagulation; Oxidative stress; Intensive care; heart rate variability; Variability; Young adult; Inflammation; Urban area; air pollution; Resuscitation

The biological mechanisms linking air pollution to cardiovascular events still remain largely unclear. To investigate whether biological mechanisms linking air pollution to cardiovascular events occurred concurrently in human subjects exposed to urban air pollutants. We recruited a panel of 76 young...