Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells

Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid th...

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Bibliographic Details
Published inJournal of fermentation and bioengineering Vol. 83; no. 2; pp. 157 - 160
Main Authors Chan, Err-Cheng, Cheng, Chin-Sheng, Hsu, Yuan-Hsun
Format Journal Article
LanguageEnglish
Published Osaka Elsevier B.V 01.01.1997
Society for Fermentation and Bioengineering
Subjects
13-dicarboxylic acid
bioconversion
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Pseudomonas aeruginosa
13-dicarboxylic acid
1
Pseudomonas aeruginosa
bioconversion
Pseudomonadales
Surfactant
Optimization
Continuous process
Chemical treatment
Biotransformation
Alkane
Production
Bacteria
Pseudomonadaceae
Dicarboxylic acid
Yield
Entrapped microorganism
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Summary:Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0922-338X
DOI:10.1016/S0922-338X(97)83575-1