Cardiovascular comorbidity and its impact on patients with COVID-19

We truly appreciate the comments from C.E. Leiva Sisnieguez and colleagues, who have performed a further analysis on the potential association between cardiovascular comorbidities and the clinical outcomes of coronavirus disease 2019 (COVID-19), particularly the mortality). We also applaud the sugge...

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Bibliographic Details
Published inThe European respiratory journal Vol. 55; no. 6; p. 2001227
Main Authors Guan, Wei-jie, Liang, Wen-hua, He, Jian-xing, Zhong, Nan-shan
Format Journal Article
LanguageEnglish
Published England European Respiratory Society 01.06.2020
Subjects
Agora
Betacoronavirus
China
Comorbidity
Coronavirus Infections - epidemiology
COVID-19
Humans
Pandemics
Pneumonia, Viral
SARS-CoV-2
China
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Summary:We truly appreciate the comments from C.E. Leiva Sisnieguez and colleagues, who have performed a further analysis on the potential association between cardiovascular comorbidities and the clinical outcomes of coronavirus disease 2019 (COVID-19), particularly the mortality). We also applaud the suggestion to thoroughly adjust for potential confounding factors when interpreting the association between specific categories of cardiovascular comorbidities ( e.g. hypertension) and the clinical outcomes of COVID-19. To this end, we have attempted to incorporate the cardiovascular diseases (including coronary heart disease) into the multivariate regression model [1]. Findings of the model indicated a prominent collinearity between hypertension and coronary heart disease, and we have therefore elected to retain hypertension in the regression model for further analyses. Comorbid hypertension correlates with poorer outcomes in patients with COVID-19 https://bit.ly/2zoT9f0
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
ObjectType-Commentary-2
content type line 23
ISSN:0903-1936
1399-3003
1399-3003
DOI:10.1183/13993003.01227-2020