A dog with myelodysplastic syndrome: Chronic myelomonocytic leukemia

An eleven-year-old female pug was referred to Yamaguchi University Animal Hospital for evaluation of anemia and thrombocytopenia. The cytological examination of the peripheral blood showed some giant monocytic lineage blast cells. A few granulocytes and platelets had dysplastic features. On day 7, i...

Full description

Saved in:
Bibliographic Details
Published inJournal of Veterinary Medical Science Vol. 69; no. 6; pp. 665 - 668
Main Authors Hiraoka, H.(Yamaguchi Univ. (Japan). Faculty of Agriculture), Hisasue, M, Nagashima, N, Miyama, T, Tanimoto, T, Watanabe, M, Itamoto, K, Mizuno, T, Inokuma, H, Okuda, M
Format Journal Article
LanguageEnglish
Published Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.06.2007
Subjects
Animals
BLOOD DISORDERS
BONE MARROW
CHIEN
Cyclosporine - therapeutic use
DISPLASIA
Dog Diseases - diagnosis
Dog Diseases - drug therapy
Dog Diseases - pathology
DOGS
DYSPLASIA
DYSPLASIE
dysplastic features
Female
Immunosuppressive Agents - therapeutic use
Leukemia, Myelomonocytic, Chronic - diagnosis
Leukemia, Myelomonocytic, Chronic - drug therapy
Leukemia, Myelomonocytic, Chronic - pathology
Leukemia, Myelomonocytic, Chronic - veterinary
MDSs
MEDULA OSEA
MOELLE OSSEUSE
MONOCITOSIS
MONOCYTOSE
MONOCYTOSIS
PERRO
TRASTORNOS SANGUINEOS
TROUBLE SANGUIN
Online AccessGet full text

Cover

More Information
Summary:An eleven-year-old female pug was referred to Yamaguchi University Animal Hospital for evaluation of anemia and thrombocytopenia. The cytological examination of the peripheral blood showed some giant monocytic lineage blast cells. A few granulocytes and platelets had dysplastic features. On day 7, in addition to increasing the monocytic lineage cells, the dysplastic features of the blood had also increased compared to the initial examination. We performed bone marrow aspiration upon her death. The bone marrow revealed dysplastic features in all three hematopoietic cell lines, and an increase in the monocytic cell line. Based on the features of the bone marrow and the peripheral blood, this case was confirmed to be myelodysplastic syndrome-Chronic myelomonocytic leukaemia (MDS-CMML).
Bibliography:L70
2007009530
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.69.665