3-Dimensional Echocardiography and 2-D Strain Analysis of Left Ventricular, Left Atrial and Right Ventricular Function in Healthy Brazilian Volunteers

• Published in: Arquivos brasileiros de cardiologia Vol. 113; no. 5; pp. 935 - 945
• Main Authors: Saraiva, Roberto M, Scolin, Eliza Maria B, Pacheco, Nicole P, Bouret, Maria Eduarda, Mediano, Mauro Felippe Felix, Holanda, Marcelo T, Costa, Andréa R da
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Cardiologia - SBC 01.11.2019; Sociedade Brasileira de Cardiologia (SBC)
• Subjects: Adolescent; Adult; Age Factors; Aged; Atrial Function, Left; Brazil; CARDIAC & CARDIOVASCULAR SYSTEMS; Cross-Sectional Studies; Doenças Cardiovasculares; Echocardiography - methods; Echocardiography - standards; Echocardiography, Three-Dimensional - methods; Echocardiography, Three-Dimensional - standards; Ecocardiografia Tridimensional; Female; Função Ventricular Direita; Função Ventricular Esquerda; Healthy Volunteers; Humans; Male; Middle Aged; Original; Prospective Studies; Reference Values; Sex Factors; Speckle Tracking; Strain; Valores de Referência; Ventricular Function, Left; Ventricular Function, Right; Young Adult; Brazil; Função Ventricular Direita; Cardiovascular Diseases; Speckle Tracking; Right Ventricular Function; Valores de Referência; Ecocardiografia Tridimensional; Echocardiography, Three-Dimensional; Reference Values; Doenças Cardiovasculares; Função Ventricular Esquerda; Left Ventricular Function; Strain
• ISSN: 0066-782X; 1678-4170; 1678-4170
• DOI: 10.5935/abc.20190155

New echocardiographic techniques are used in the diagnosis and prognosis of many heart diseases. However, reference values in different populations are still needed for several of these new indexes. We studied these new echocardiographic parameters in a group of Brazilians with no known cardiovascular disease. To study values for new echocardiographic indexes in Brazilians without known cardiovascular disease and their correlation with age. Cross-sectional study that included healthy individuals who underwent three-dimensional echocardiography (3DE) and two-dimensional speckle tracking echocardiography (STE) strain (e) analysis. Left atrial (LA) and left ventricular (LV) function were analyzed by 3DE and STE, and right ventricular (RV) function by STE. P values < 0.05 were considered significant. Seventy-seven subjects (46.7% men; 40.4 ± 10.4 years) were included. Maximum, minimum and pre-atrial contraction (pre-A) LA volumes (ml/m2) were 21.2 ± 5.5, 7.8 ± 2.5, and 11.0 ± 3.1, respectively. Peak positive global LA e (LAScd), peak negative global LA e and total global LA e (LASr) were 17.4 ± 5.2%, -13.2 ± 2.0% and 30.5 ± 5.9%, respectively. LV end-diastolic and end-systolic volumes (ml/m2) measured 57 ± 12 and 24 ± 6, and 3D LV ejection fraction measured 58 ± 6%. Global LV longitudinal, circumferential and radial e were -19 ± 2%, -19 ± 3%, and 46 ± 12%, respectively. LV torsion measured 1.6 ± 0.70 /cm. Global longitudinal RV e (RV-GLS) and RV free wall strain were -22 ± 3% and -24 ± 5%. Minimum LA and pre-A volumes, LV apical rotation, torsion and RV-GLS increased with age, while total and passive LA emptying fractions, LAScd, LASr, LV end-diastolic and end-systolic volumes decreased with age. Values for new echocardiographic indexes in Brazilians without known cardiovascular disease and their correlation with age are presented.