Thromboxane B2 production during erection

The effect of erection on 6-keto-PGF1 alpha and thromboxane B2 in penile blood during electrically evoked erection was studied in the chacma baboon. 6-keto-PGF1 alpha remained at a low concentration, but thromboxane B2 showed a statistically significant rise 8-10 minutes after commencement of erecti...

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Bibliographic Details
Published inAndrologia Vol. 18; no. 2; p. 220
Main Authors Bornman, M S, Franz, R C, Jacobs, D J, Du Plessis, D J
Format Journal Article
LanguageEnglish
Published Germany 01.03.1986
Subjects
6-Ketoprostaglandin F1 alpha - blood
Aging
Animals
Erectile Dysfunction - etiology
Male
Papio
Penile Erection
Platelet Aggregation
Thromboxane B2 - blood
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Summary:The effect of erection on 6-keto-PGF1 alpha and thromboxane B2 in penile blood during electrically evoked erection was studied in the chacma baboon. 6-keto-PGF1 alpha remained at a low concentration, but thromboxane B2 showed a statistically significant rise 8-10 minutes after commencement of erection. Elevated thromboxane B2 during erection may potentiate platelet aggregation and may be one of the key events in the pathogenesis of ageing impotence.
ISSN:0303-4569
DOI:10.1111/j.1439-0272.1986.tb01766.x