Assessment of genetically modified soybean MON 87751 for food and feed uses under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2014‐121)

• Published in: EFSA journal Vol. 16; no. 8; pp. e05346 - n/a
• Main Authors: Naegeli, Hanspeter, Birch, Andrew Nicholas, Casacuberta, Josep, De Schrijver, Adinda, Gralak, Mikołaj Antoni, Jones, Huw, Manachini, Barbara, Messéan, Antoine, Nielsen, Elsa Ebbesen, Nogué, Fabien, Robaglia, Christophe, Rostoks, Nils, Sweet, Jeremy, Tebbe, Christoph, Visioli, Francesco, Wal, Jean‐Michel, Álvarez, Fernando, Ardizzone, Michele, Fernandez Dumont, Antonio, Gómez Ruiz, José Ángel, Papadopoulou, Nikoletta, Paraskevopoulos, Konstantinos
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.08.2018; John Wiley and Sons Inc; Wiley
• Subjects: Accidental release; Allergenicity; Animal health; Cry1A.105; Cry2Ab2; Environmental monitoring; Food; Food safety; Genetic modification; Genetic transformation; Genetically altered foods; Genetically modified organisms; GMO; insect resistant; MON 87751; Pests; Proteins; Regulation (EC) No 1829/2003; Risk assessment; Safety; Scientific Opinion; Seeds; soybean (Glycine max); Soybeans; Toxicity; insect resistant; soybean (Glycine max); Cry2Ab2; Regulation (EC) No 1829/2003; GMO; Cry1A.105; MON 87751
• ISSN: 1831-4732; 1831-4732; 2314-9396
• DOI: 10.2903/j.efsa.2018.5346

Soybean MON 87751 was developed through Agrobacterium tumefaciens‐mediated transformation to provide protection certain specific lepidopteran pests by the expression of the Cry1A.105 and Cry2Ab2 proteins derived from Bacillus thuringiensis. The molecular characterisation data and bioinformatic analyses did not identify issues requiring assessment for food and feed safety. None of the compositional, agronomic and phenotypic differences identified between soybean MON 87751 and the conventional counterpart required further assessment. The GMO Panel did not identify safety concerns regarding the toxicity and allergenicity of the Cry1A.105 and Cry2Ab2 proteins as expressed in soybean MON 87751, and found no evidence that the genetic modification might significantly change the overall allergenicity of soybean MON 87751. The nutritional impact of soybean MON 87751‐derived food and feed is expected to be the same as those derived from the conventional counterpart and non‐GM commercial reference varieties. The GMO Panel concludes that soybean MON 87751, as described in this application, is nutritionally equivalent to and as safe as the conventional counterpart and the non‐GM soybean reference varieties tested, and no post‐market monitoring of food and feed is considered necessary. In the case of accidental release of viable soybean MON 87751 seeds into the environment, soybean MON 87751 would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean MON 87751. In conclusion, soybean MON 87751, as described in this application, is as safe as its conventional counterpart and the tested non‐GM soybean reference varieties with respect to potential effects on human and animal health and the environment.